Propofol Infusion Syndrome— Report of an Adult Fatality
نویسندگان
چکیده
منابع مشابه
Suggested beginning of propofol infusion syndrome in an adult patient without lactacidosis: a case report.
EDITOR: Propofol infusion syndrome (PRIS) is a rare and often fatal disease associated with propofol sedation at doses of more than 5 mg kg h for more than 48 h. PRIS is characterized by lipaemic plasma, fatty liver enlargement, metabolic acidosis, rhabdomyolysis or myoglobinuria, cardiac arrhythmia and acute bradycardia progressing to asystole. The syndrome usually occurs in patients with cent...
متن کاملPropofol infusion syndrome.
The clinical features of propofol infusion syndrome (PRIS) are acute refractory bradycardia leading to asystole, in the presence of one or more of the following: metabolic acidosis (base deficit > 10 mmol.l(-1)), rhabdomyolysis, hyperlipidaemia, and enlarged or fatty liver. There is an association between PRIS and propofol infusions at doses higher than 4 mg.kg(-1).h(-1) for greater than 48 h d...
متن کاملPropofol Infusion Syndrome or Probable Overinterpretation Syndrome?
To the Editor:—It was with great interest that we read the article by Cravens et al. on the incidence of propofol infusion syndrome. This is obviously an important question with significant clinical relevance. However, with all of the inherent limitations of a retrospective study as recognized by the authors, we find the interpretation and conclusion of the authors (“this study provides evidenc...
متن کاملPropofol infusion syndrome or probable overinterpretation syndrome?
To the Editor:—It was with great interest that we read the article by Cravens et al. on the incidence of propofol infusion syndrome. This is obviously an important question with significant clinical relevance. However, with all of the inherent limitations of a retrospective study as recognized by the authors, we find the interpretation and conclusion of the authors (“this study provides evidenc...
متن کاملPropofol Infusion Syndrome in Refractory Status Epilepticus
BACKGROUND AND PURPOSE Propofol is used for treating refractory status epilepticus, which has high rate of mortality. Propofol infusion syndrome is a rare but often fatal syndrome, characterized by lactic acidosis, lipidemia, and cardiac failure, associated with propofol infusion over prolonged periods of time. We investigated the clinical factors that characterize propofol infusion syndrome to...
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ژورنال
عنوان ژورنال: Anaesthesia and Intensive Care
سال: 2004
ISSN: 0310-057X,1448-0271
DOI: 10.1177/0310057x0403200303